| Date | Opponent | Location | Time/Result | |  | | Nov. 10, 2012 | vs. UNC Greensboro (Asheville Collegiate Invitational)  | Asheville, N.C. | 60-57 W | Recap | Box | | Nov. 14, 2012 | Southern Wesleyan | Charleston, S.C. | 84-52 W | Recap | Box | | Nov. 20, 2012 | @ N.C. State | Raleigh, N.C. | 54-81 L | Recap | Box | | Nov. 24, 2012 | Paine | Charleston, S.C. | 82-70 W | Recap | Box | | Nov. 28, 2012 | @ Presbyterian* | Clinton, S.C. | 57-58 L | Recap | Box | | Dec. 1, 2012 | @ Wake Forest | Winston-Salem, N.C. | 57-77 L | Recap | Box | | Dec. 12, 2012 | S.C. State | Charleston, S.C. | 57-73 L | Recap | Box | | Dec. 17, 2012 | Trinity Baptist | Charleston, S.C. | 71-46 W | Recap | Box | | Dec. 19, 2012 | Western Carolina | Charleston, S.C. | 69-61 W | Recap | Box | | Dec. 31, 2012 | College of Charleston | Charleston, S.C. | 45-76 L | Recap | Box | | Jan. 3, 2013 | @ High Point* | High Point, N.C. | 54-71 L | Recap | Box | | Jan. 5, 2013 | @ Coastal Carolina* | Conway, S.C. | 56-64 L | Recap | Box | | Jan. 10, 2013 | Liberty* | Charleston, S.C. | 33-92 L | Recap | Box | | Jan. 12, 2013 | Longwood* | Charleston, S.C. | 52-67 L | Recap | Box | | Jan. 17, 2013 | @ Winthrop* | Rock Hill, S.C. | 65-85 L | Recap | Box | | Jan. 19, 2013 | @ Radford* | Radford, Va. | 60-71 L | Recap | Box | | Jan. 24, 2013 | UNC Asheville* | Charleston, S.C. | 73-59 W | Recap | Box | | Jan. 26, 2013 | Gardner-Webb* | Charleston, S.C. | 55-59 L | Recap | Box | | Jan. 31, 2013 | Radford* | Charleston, S.C. | 57-64 L | Recap | Box | | Feb. 2, 2013 | Winthrop* | Charleston, S.C. | 65-73 L | Recap | Box | | Feb. 7, 2013 | @ UNC Asheville* | Asheville, N.C. | 54-48 W | Recap | Box | | Feb. 9, 2013 | @ Gardner-Webb (ESPN3)* | Boiling Springs, N.C. | 55-48 W | Recap | Box | | Feb. 16, 2013 | Presbyterian* | Charleston, S.C. | 61-79 L | Recap | Box | | Feb. 21, 2013 | Coastal Carolina* | Charleston, S.C. | (OT) 72-77 L | Recap | Box | | Feb. 23, 2013 | Campbell* | Charleston, S.C. | 55-65 L | Recap | Box | | Feb. 28, 2013 | @ Longwood* | Farmville, Va. | 73-79 L | Recap | Box | | Mar. 2, 2013 | @ Liberty* | Lynchburg, Va. | 62-88 L | Recap | Box | | Mar. 6, 2013 | vs. No. 7 Longwood (VisitMyrtleBeach.com Big South Championship) | Conway, S.C. (The HTC Center) | 63-70 L | Recap | Box |
| | Record: 8-20 (3-15 BSC) Home events are in bold.
* - indicates Big South Conference event
All times are Eastern. |
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